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found that autophagy is a catabolic self-feeding pathway that is emerging as a key integration point in cellular physiology (Wang et al., 2024b)
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however, EAS enzymes are deactivated due to chronic elevated H 2 O 2 induced by defective mitochondria (Schallreuter, 2014)
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B12 insufficiency impairs MTR function regardless of 5-MTHF availability
The majority of existing studies utilize transplantation methods (Khling et al., 2006
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